Next generation sequencing of PD-L1 for predicting response to immune checkpoint inhibitors

BACKGROUND: PD-L1 immunohistochemistry (IHC) has been traditionally used for predicting clinical responses to immune checkpoint inhibitors (ICIs). However, there are at least 4 different assays and antibodies used for PD-L1 IHC, each developed with a different ICI. We set to test if next generation...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Conroy, Jeffrey M., Pabla, Sarabjot, Nesline, Mary K., Glenn, Sean T., Papanicolau-Sengos, Antonios, Burgher, Blake, Andreas, Jonathan, Giamo, Vincent, Wang, Yirong, Lenzo, Felicia L., Bshara, Wiam, Khalil, Maya, Dy, Grace K., Madden, Katherine G., Shirai, Keisuke, Dragnev, Konstantin, Tafe, Laura J., Zhu, Jason, Labriola, Matthew, Marin, Daniele, McCall, Shannon J., Clarke, Jeffrey, George, Daniel J., Zhang, Tian, Zibelman, Matthew, Ghatalia, Pooja, Araujo-Fernandez, Isabel, de la Cruz-Merino, Luis, Singavi, Arun, George, Ben, MacKinnon, Alexander C., Thompson, Jonathan, Singh, Rajbir, Jacob, Robin, Kasuganti, Deepa, Shah, Neel, Day, Roger, Galluzzi, Lorenzo, Gardner, Mark, Morrison, Carl
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346512/
https://ncbi.nlm.nih.gov/pubmed/30678715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0489-5
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