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Zebrafish Granulocyte Colony-Stimulating Factor Receptor Maintains Neutrophil Number and Function throughout the Life Span

Granulocyte colony-stimulating factor receptor (G-CSFR), encoded by the CSF3R gene, represents a major regulator of neutrophil production and function in mammals, with inactivating extracellular mutations identified in a cohort of neutropenia patients unresponsive to G-CSF treatment. This study soug...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Basheer, Faiza, Rasighaemi, Parisa, Liongue, Clifford, Ward, Alister C.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346135/
https://ncbi.nlm.nih.gov/pubmed/30455199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00793-18
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