Impaired activation of lesional CD8(+) T-cells is associated with enhanced expression of Programmed Death-1 in Indian Post Kala-azar Dermal Leishmaniasis

Post Kala-azar dermal leishmaniasis (PKDL), caused by Leishmania donovani is the dermal sequel of Visceral Leishmaniasis and importantly, is the proposed disease reservoir. The survival of Leishmania parasites within monocytes/macrophages hinges on its ability to effectively nullify immune activatio...

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Vydáno v:Sci Rep
Hlavní autoři: Mukherjee, Shibabrata, Sengupta, Ritika, Mukhopadhyay, Debanjan, Braun, Claudia, Mitra, Sneha, Roy, Susmita, Kanti Das, Nilay, Chatterjee, Uttara, von Stebut, Esther, Chatterjee, Mitali
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345993/
https://ncbi.nlm.nih.gov/pubmed/30679687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37144-y
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