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Neuropathological correlates and genetic architecture of microglial activation in elderly human brain

Microglia, the resident immune cells of the brain, have important roles in brain health. However, little is known about the regulation and consequences of microglial activation in the aging human brain. Here we report that the proportion of morphologically activated microglia (PAM) in postmortem cor...

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Publicado en:Nat Commun
Autores principales: Felsky, Daniel, Roostaei, Tina, Nho, Kwangsik, Risacher, Shannon L., Bradshaw, Elizabeth M., Petyuk, Vlad, Schneider, Julie A., Saykin, Andrew, Bennett, David A., De Jager, Philip L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345810/
https://ncbi.nlm.nih.gov/pubmed/30679421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08279-3
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