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Clinical Metagenomic Next-Generation Sequencing for Pathogen Detection

Nearly all infectious agents contain DNA or RNA genomes, making sequencing an attractive approach for pathogen detection. The cost of high-throughput or next-generation sequencing has been reduced by several orders of magnitude since its advent in 2004, and it has emerged as an enabling technologica...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Annu Rev Pathol
Hauptverfasser: Gu, Wei, Miller, Steve, Chiu, Charles Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345613/
https://ncbi.nlm.nih.gov/pubmed/30355154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pathmechdis-012418-012751
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