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The GTPase Rab1 is required for NLRP3 inflammasome activationand inflammatory lung injury

Uncontrolled inflammatory response during sepsis predominantly contributes to the development of multi-organ failure and lethality. However, the cellular and molecular mechanisms for excessive production and release of proinflammatory cytokines are not clearly defined. Here, we show the crucial role...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Zhang, Yuehui, Wang, Lijun, Lv, Yang, Jiang, Chunling, Wu, Guangyu, Dull, Randal O., Minshall, Richard D., Malik, Asrar B., Hu, Guochang
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345506/
https://ncbi.nlm.nih.gov/pubmed/30455398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800777
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