Bacterial regulation of macrophage bacterial recognition receptors in COPD are differentially modified by budesonide and fluticasone propionate

RATIONALE: Patients with COPD have an increased risk for community-acquired pneumonia, which is further increased by inhaled corticosteroids. OBJECTIVE: To assess effects of the corticosteroids, budesonide and fluticasone propionate, on macrophage bacterial responses in COPD. METHODS: Monocyte-deriv...

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Pubblicato in:PLoS One
Autori principali: Provost, Karin A., Smith, Miyuki, Miller-Larsson, Anna, Gudleski, Gregory D., Sethi, Sanjay
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345465/
https://ncbi.nlm.nih.gov/pubmed/30677037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207675
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