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Reduction in IGF1 mRNA in the Human Subependymal Zone During Aging

The cell proliferation marker, Ki67 and the immature neuron marker, doublecortin are both expressed in the major human neurogenic niche, the subependymal zone (SEZ), but expression progressively decreases across the adult lifespan (PMID: 27932973). In contrast, transcript levels of several mitogens...

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Detalhes bibliográficos
Publicado no:Aging Dis
Main Authors: Weissleder, Christin, Barry, Guy, Fung, Samantha J., Wong, Matthew W., Double, Kay L., Webster, Maree J., Weickert, Cynthia Shannon
Formato: Artigo
Idioma:Inglês
Publicado em: JKL International LLC 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345338/
https://ncbi.nlm.nih.gov/pubmed/30705779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2018.0317
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