Cerebrospinal fluid levels of glial marker YKL-40 strongly associated with axonal injury in HIV infection

BACKGROUND: HIV-1 infects the central nervous system (CNS) shortly after transmission. This leads to a chronic intrathecal immune activation. YKL-40, a biomarker that mainly reflects activation of astroglial cells, has not been thoroughly investigated in relation to HIV. The objective of our study w...

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Publicat a:J Neuroinflammation
Autors principals: Hermansson, Linn, Yilmaz, Aylin, Axelsson, Markus, Blennow, Kaj, Fuchs, Dietmar, Hagberg, Lars, Lycke, Jan, Zetterberg, Henrik, Gisslén, Magnus
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345016/
https://ncbi.nlm.nih.gov/pubmed/30678707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1404-9
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