Methylation of IL-2 promoter at birth alters the risk of asthma exacerbations during childhood

BACKGROUND: Epigenetic modifications may have a role in asthma susceptibility. OBJECTIVE: To investigate whether epigenetic modification at birth of a CpG site necessary for the regulation of IL-2 transcription (IL-2 Site1) is associated with the development of asthma during childhood. METHODS: Meth...

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Bibliografiset tiedot
Julkaisussa:Clin Exp Allergy
Päätekijät: Curtin, J. A., Simpson, A., Belgrave, D., Semic-Jusufagic, A., Custovic, A., Martinez, F. D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344940/
https://ncbi.nlm.nih.gov/pubmed/23414538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.12046
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