Avocado (Persea americana) fruit extract (2R,4R)-1,2,4-trihydroxyheptadec-16-yne inhibits dengue virus replication via upregulation of NF-κB–dependent induction of antiviral interferon responses

Dengue virus (DENV) caused millions of infections around the world annually. Co-infection with different serotypes of DENV is associated with dengue hemorrhagic shock syndrome, leading to an estimate of 50% death rate. No approved therapies are currently available for the treatment of DENV infection...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Wu, Yu-Hsuan, Tseng, Chin-Kai, Wu, Ho-Cheng, Wei, Chih-Ku, Lin, Chun-Kuang, Chen, Ih-Sheng, Chang, Hsun-Shuo, Lee, Jin-Ching
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344542/
https://ncbi.nlm.nih.gov/pubmed/30674997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36714-4
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