Central Adiponectin Induces Trabecular Bone Mass partly through Epigenetic downregulation of Cannabinoid Receptor CB1

Central adiponectin (APN) in either the globular (gAPN) or full-length (fAPN) forms decrease sympathetic tone and increase trabecular bone mass in mice through the hypothalamus. It is known that cannabinoid type-1 (CB1) receptors are expressed in the hypothalamic ventromedial nucleus (VMN) and parti...

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Veröffentlicht in:J Cell Physiol
Hauptverfasser: Jiang, Hua, Wu, Yuwei, Valverde, Paloma, Murray, Dana, Tang, Jin, Yao, Qi, Han, Qianqian, Zhang, Jin, Zhang, Lan, Sui, Lei, Tang, Yin, Tu, Qisheng, Chen, Jake
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344306/
https://ncbi.nlm.nih.gov/pubmed/30479003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.27460
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