Dopamine receptor D2, but not D1, mediates descending dopaminergic pathway-produced analgesic effect in a trigeminal neuropathic pain mouse model

Neuropathic pain represents a challenge to clinicians, because it is resistant to commonly prescribed analgesics due to its largely unknown mechanisms. Here, we investigated a descending dopaminergic pathway-mediated modulation of trigeminal neuropathic pain. We performed chronic constriction injury...

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Publicado en:Pain
Main Authors: Liu, Sufang, Tang, Yuanyuan, Shu, Hui, Tatum, Delton, Bai, Qian, Crawford, Joshua, Xing, Ying, Lobo, Mary Kay, Bellinger, Larry, Kramer, Phillip, Tao, Feng
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344251/
https://ncbi.nlm.nih.gov/pubmed/30325872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001414
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