Nicotine improves probabilistic reward learning in wildtype but not alpha7 nAChR null mutants, yet alpha7 nAChR agonists do not improve probabilistic learning.

Cognitive impairments, e.g., reward learning, are present in various psychiatric disorders and warrant treatment. Improving reward-related learning could synergistically enhance psychosocial treatments and cognition generally. A critical first step is to understand the mechanisms underlying reward l...

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Pubblicato in:Eur Neuropsychopharmacol
Autori principali: Milienne-Petiot, Morgane, Higa, Kerin K, Grim, Andrea, Deben, Debbie, Groenink, Lucianne, Twamley, Elizabeth W., Geyer, Mark A., Young, Jared W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344043/
https://ncbi.nlm.nih.gov/pubmed/30213668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euroneuro.2018.08.005
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