Schweinfurthin natural products induce regression of murine melanoma and pair with anti-PD-1 therapy to facilitate durable tumor immunity

Metastatic melanoma is a significant clinical problem with a 5-year survival rate of only 15–20%. Recent approval of new immunotherapies and targeted inhibitors have provided much needed options for these patients, in some cases promoting dramatic disease regressions. In particular, antibody-based t...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Kokolus, Kathleen M., Haley, Jeremy S., Koubek, Emily J., Gowda, Raghavendra, Dinavahi, Saketh S., Sharma, Arati, Claxton, David F., Helm, Klaus F., Drabick, Joseph J., Robertson, Gavin P., Neighbors, Jeffrey D., Hohl, Raymond J., Schell, Todd D.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343772/
https://ncbi.nlm.nih.gov/pubmed/30713799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1539614
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