Batf3(+) DCs and type I IFN are critical for the efficacy of neoadjuvant cancer immunotherapy

New clinical trials are now evaluating the efficacy of neoadjuvant immunotherapy in the context of primary tumor surgery. Using the orthotopic 4T1.2 mouse model of spontaneously metastatic mammary cancer, we have shown that neoadjuvant immunotherapy and surgery was superior in the generation of tumo...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Liu, Jing, Rozeman, Elisa A., O’Donnell, Jake S., Allen, Stacey, Fanchi, Lorenzo, Smyth, Mark J., Blank, Christian U., Teng, Michele W.L.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343771/
https://ncbi.nlm.nih.gov/pubmed/30713806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1546068
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