Modulator-Gated, SUMOylation-Mediated, Activity-Dependent Regulation of Ionic Current Densities Contributes to Short-Term Activity Homeostasis

Neurons operate within defined activity limits, and feedback control mechanisms dynamically tune ionic currents to maintain this optimal range. This study describes a novel, rapid feedback mechanism that uses SUMOylation to continuously adjust ionic current densities according to changes in activity...

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Publicat a:J Neurosci
Autors principals: Parker, Anna R., Forster, Lori A., Baro, Deborah J.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343643/
https://ncbi.nlm.nih.gov/pubmed/30504282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1379-18.2018
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