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Genetic alterations affecting GTPases and T-cell receptor signaling in peripheral T-cell lymphomas

Peripheral T-cell lymphomas (PTCLs) are rare, heterogeneous tumors with poor response to standard therapy and few targeted treatments available. The identification of mutations in the T-cell receptor (TCR) signaling pathway that either directly or indirectly affect Ras- and Rho-family GTPases is an...

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Dades bibliogràfiques
Publicat a:Small GTPases
Autors principals: Boddicker, Rebecca L., Razidlo, Gina L., Feldman, Andrew L.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343532/
https://ncbi.nlm.nih.gov/pubmed/27898263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1263718
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