HLA-DQ strikes again: Genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults

BACKGROUND: Asthma is a common chronic respiratory disease in children and adults. An important genetic component to asthma susceptibility has long been recognized, most recently through the identification of several genes (e.g., ORMDL3, PDE4D, HLA-DQ, and TLE4) via genome-wide association studies....

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Udgivet i:Clin Exp Allergy
Main Authors: Lasky-Su, J., Himes, B. E., Raby, B. A., Klanderman, B. J., Sylvia, J. Senter, Lange, C., Melen, E., Martinez, F. D., Israel, E., Gauderman, J., Gilliland, F., Sleiman, P., Hakonarson, H., Celedόn, J. C., Soto-Quiros, M., Avila, L., Lima, J. J., Irvin, C. G., Peters, S. P., Boushey, H., Chinchilli, V. M., Mauger, D., Tantisira, K., Weiss, S. T.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343489/
https://ncbi.nlm.nih.gov/pubmed/23181788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.12000
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