Molecular characterization and mapping of glucose-6-phosphate dehydrogenase (G6PD) mutations in the Greater Mekong Subregion

BACKGROUND: Plasmodium vivax malaria elimination can only be achieved by the deployment of 8-aminoquinolines (primaquine and tafenoquine) in combination with ACT to kill both blood and liver-stage parasites. However, primaquine and the other 8-aminoquinolines cause dose-dependent haemolysis in subje...

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Foilsithe in:Malar J
Main Authors: Bancone, Germana, Menard, Didier, Khim, Nimol, Kim, Saorin, Canier, Lydie, Nguong, Chea, Phommasone, Koukeo, Mayxay, Mayfong, Dittrich, Sabine, Vongsouvath, Malavanh, Fievet, Nadine, Le Hesran, Jean-Yves, Briand, Valerie, Keomany, Sommay, Newton, Paul N., Gorsawun, Gornpan, Tardy, Kaelan, Chu, Cindy S., Rattanapalroj, Orpreeya, Dong, Le Thanh, Quang, Huynh Hong, Tam-Uyen, Nguyen, Thuy-Nhien, Nguyen, Hien, Tran Tinh, Kalnoky, Michael, Nosten, Francois
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2019
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343352/
https://ncbi.nlm.nih.gov/pubmed/30674319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-019-2652-y
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