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Cancer cell migration on elongate protrusions of fibroblasts in collagen matrix

Cancer-associated fibroblasts (CAFs) play critical roles in the tumor progression. However, it remains unclear how cancer cells migrate in the three-dimensional (3D) matrix of cancer tissues and how CAFs support the cancer invasion. Here we propose a novel mechanism of fibroblast-dependent cancer ce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Miyazaki, Kaoru, Oyanagi, Jun, Hoshino, Daisuke, Togo, Shinsaku, Kumagai, Hiromichi, Miyagi, Yohei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342997/
https://ncbi.nlm.nih.gov/pubmed/30670761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36646-z
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