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Effects of point mutations in the binding pocket of the mouse major urinary protein MUP20 on ligand affinity and specificity

The mouse Major Urinary Proteins (MUPs) contain a conserved β-barrel structure with a characteristic central hydrophobic pocket that binds a variety of volatile compounds. After release of urine, these molecules are slowly emitted in the environment where they play an important role in chemical comm...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Ricatti, Jimena, Acquasaliente, Laura, Ribaudo, Giovanni, De Filippis, Vincenzo, Bellini, Marino, Llovera, Ramiro Esteban, Barollo, Susi, Pezzani, Raffaele, Zagotto, Giuseppe, Persaud, Krishna C., Mucignat-Caretta, Carla
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342991/
https://ncbi.nlm.nih.gov/pubmed/30670733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36391-3
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