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Inhibition of Tissue-Nonspecific Alkaline Phosphatase Attenuates Ectopic Mineralization in the Abcc6(−/−) Mouse Model of PXE but not in the Enpp1 Mutant Mouse Models of GACI
Pseudoxanthoma elasticum (PXE), a prototype of heritable ectopic mineralization disorders, is caused by mutations in the ABCC6 gene encoding a putative efflux transporter ABCC6. It was recently demonstrated that the absence of ABCC6-mediated ATP release from the liver, and consequently reduced PPi l...
Zapisane w:
| Wydane w: | J Invest Dermatol |
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| Główni autorzy: | , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6342656/ https://ncbi.nlm.nih.gov/pubmed/30130617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2018.07.030 |
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