Polygenic risk scores derived from a Tourette syndrome GWAS predict presence of tics in the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort

BACKGROUND: Tourette syndrome (TS) has a well-established genetic background, but its genetic architecture remains largely unknown. The authors investigated the role of polygenic risk scores (PRS) derived from a TS genome-wide association study (GWAS) in relation to the occurrence of tics and associ...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Abdulkadir, Mohamed, Mathews, Carol A., Scharf, Jeremiah M., Yu, Dongmei, Tischfield, Jay A., Heiman, Gary A., Hoekstra, Pieter J., Dietrich, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342633/
https://ncbi.nlm.nih.gov/pubmed/30424865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2018.09.011
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