Improving peak concentrations of a single dose regime of gentamicin in patients with sepsis in the emergency department

OBJECTIVE: To achieve an optimal effect in patients with sepsis at the emergency department (ED), the gentamicin peak-concentration should be sufficiently high (i.e. peak-concentration/MIC ≥8–10). ICU patients with sepsis often need higher gentamicin doses to achieve sufficiently high peak-concentra...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Cobussen, Maarten, Stassen, Patricia M., Posthouwer, Dirk, van Tiel, Frank H., Savelkoul, Paul H. M., Havenith, Thomas, Haeseker, Michiel B.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342306/
https://ncbi.nlm.nih.gov/pubmed/30668571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210012
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