MSC-derived exosomes promote proliferation and inhibit apoptosis of chondrocytes via lncRNA-KLF3-AS1/miR-206/GIT1 axis in osteoarthritis

Background: Exosomes secreted by human mesenchymal stem cells (hMSCs) have been shown to promote cartilage regeneration. This study aimed to explore whether exosomal lncRNA-KLF3-AS1 derived from hMSCs can promote chondrocyte proliferation via miR-206/GIT1 axis in osteoarthritis (OA). Methods: hMSCs...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Cycle
Autori principali: Liu, Yubao, Lin, Lupan, Zou, Rui, Wen, Chuanyang, Wang, Zhen, Lin, Fuqing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342066/
https://ncbi.nlm.nih.gov/pubmed/30324848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1526603
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