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Loss of cytosolic Mg(2+) binding sites in the Thermotoga maritima CorA Mg(2+) channel is not sufficient for channel opening

The CorA Mg(2+) channel is a homopentamer with five-fold symmetry. Each monomer consists of a large cytoplasmic domain and two transmembrane helices connected via a short periplasmic loop. In the Thermotoga maritima CorA crystal structure, a Mg(2+) is bound between D89 of one monomer and D253 of the...

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Bibliografische gegevens
Gepubliceerd in:Biochim Biophys Acta Gen Subj
Hoofdauteurs: Kowatz, Thomas, Maguire, Michael E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342003/
https://ncbi.nlm.nih.gov/pubmed/30293964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2018.09.001
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