A cysteine protease–like domain enhances the cytotoxic effects of the Photorhabdus asymbiotica toxin PaTox

The nematode mutualistic bacterium Photorhabdus asymbiotica produces a large virulence-associated multifunctional protein toxin named PaTox. A glycosyltransferase domain and a deamidase domain of this large toxin function as effectors that specifically target host Rho GTPases and heterotrimeric G pr...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Bogdanovic, Xenia, Schneider, Silvia, Levanova, Nadezhda, Wirth, Christophe, Trillhaase, Christoph, Steinemann, Marcus, Hunte, Carola, Aktories, Klaus, Jank, Thomas
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2019
Teme:
Protein Structure and Folding
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341400/
https://ncbi.nlm.nih.gov/pubmed/30478175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005043
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