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Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate

Assembly of eukaryotic ribosome is a complicated and dynamic process that involves a series of intermediates. It is unknown how the highly intertwined structure of 60S large ribosomal subunits is established. Here, we report the structure of an early nucleolar pre-60S ribosome determined by cryo-ele...

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Publié dans:Protein Cell
Auteurs principaux: Zhou, Dejian, Zhu, Xing, Zheng, Sanduo, Tan, Dan, Dong, Meng-Qiu, Ye, Keqiong
Format: Artigo
Langue:Inglês
Publié: Higher Education Press 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340896/
https://ncbi.nlm.nih.gov/pubmed/29557065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-018-0526-7
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