Outcome and prognostic factors following palliative craniospinal irradiation for leptomeningeal carcinomatosis

BACKGROUND: Leptomeningeal carcinomatosis (LC) is a severe complication of metastatic tumor spread to the central nervous system. Prognosis is dismal with a median overall survival (OS) of ~10–15 weeks. Treatment options include radiotherapy (RT) to involved sites, systemic chemo- or targeted therap...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: El Shafie, Rami A, Böhm, Karina, Weber, Dorothea, Lang, Kristin, Schlaich, Fabian, Adeberg, Sebastian, Paul, Angela, Haefner, Matthias F, Katayama, Sonja, Sterzing, Florian, Hörner-Rieber, Juliane, Löw, Sarah, Herfarth, Klaus, Debus, Jürgen, Rieken, Stefan, Bernhardt, Denise
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340499/
https://ncbi.nlm.nih.gov/pubmed/30697071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S182154
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