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Gingerenone A sensitizes the insulin receptor and increases glucose uptake by inhibiting the activity of p70 S6 kinase

SCOPE: The bioactive constituents in ginger extract responsible for their anti-hyperglycemic effect and the underlying mechanisms are incompletely understood. Gingerenone A (Gin A) has been identified as an inhibitor of p70 S6 (S6K1), a kinase that plays a critical role in the pathogenesis of insuli...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Nutr Food Res
Hauptverfasser: Chen, Junhong, Sun, Jing, Prinz, Richard A., Li, Yi, Xu, Xiulong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340301/
https://ncbi.nlm.nih.gov/pubmed/30296358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201800709
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