Crystal structure of the natural anion-conducting channelrhodopsin GtACR1

The naturally occurring channelrhodopsin variant anion channelrhodopsin-1 (ACR1), discovered in the cryptophyte algae Guillardia theta, exhibits large light-gated anion conductance and high anion selectivity when expressed in heterologous settings, properties that support its use as an optogenetic t...

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Udgivet i:Nature
Main Authors: Kim, Yoon Seok, Kato, Hideaki E., Yamashita, Keitaro, Ito, Shota, Inoue, Keiichi, Ramakrishnan, Charu, Fenno, Lief E., Evans, Kathryn E., Paggi, Joseph M., Dror, Ron O., Kandori, Hideki, Kobilka, Brian K., Deisseroth, Karl
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340299/
https://ncbi.nlm.nih.gov/pubmed/30158696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0511-6
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