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Quantitative trait mapping in Diversity Outbred mice identifies two genomic regions associated with heart size

Heart size is an important factor in cardiac health and disease. In particular, increased heart weight is predictive of adverse cardiovascular outcomes in multiple large community-based studies. We use two cohorts of Diversity Outbred (DO) mice to investigate the role of genetics, sex, age, and diet...

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Bibliografski detalji
Izdano u:Mamm Genome
Glavni autori: Shorter, John R., Huang, Wei, Beak, Ju Youn, Hua, Kunjie, Gatti, Daniel M., de Villena, Fernando Pardo‑Manuel, Pomp, Daniel, Jensen, Brian C.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340297/
https://ncbi.nlm.nih.gov/pubmed/29279960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-017-9730-7
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