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Low Levels of Human Antibodies to Gametocyte-Infected Erythrocytes Contrasts the PfEMP1-Dominant Response to Asexual Stages in P. falciparum Malaria

Vaccines that target Plasmodium falciparum gametocytes have the potential to reduce malaria transmission and are thus attractive targets for malaria control. However, very little is known about human immune responses to gametocytes present in human hosts. We evaluated naturally-acquired antibodies t...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Chan, Jo-Anne, Drew, Damien R., Reiling, Linda, Lisboa-Pinto, Ashley, Dinko, Bismarck, Sutherland, Colin J., Dent, Arlene E., Chelimo, Kiprotich, Kazura, James W., Boyle, Michelle J., Beeson, James G.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340286/
https://ncbi.nlm.nih.gov/pubmed/30692996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.03126
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