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Targeted substrate degradation by Kelch controls the actin cytoskeleton during ring canal expansion

During Drosophila oogenesis, specialized actin-based structures called ring canals form and expand to accommodate growth of the oocyte. Previous work demonstrated that Kelch and Cullin 3 function together in a Cullin 3-RING ubiquitin ligase complex (CRL3(Kelch)) to organize the ring canal cytoskelet...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Hudson, Andrew M., Mannix, Katelynn M., Gerdes, Julianne A., Kottemann, Molly C., Cooley, Lynn
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340150/
https://ncbi.nlm.nih.gov/pubmed/30559276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.169219
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