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Deletion of a specific exon in the voltage-gated calcium channel gene cacophony disrupts locomotion in Drosophila larvae

TAR DNA-binding protein 43 (TDP-43) is an RNA-binding protein that regulates transcription, translation and alternative splicing of mRNA. We have shown previously that null mutations of the Drosophila ortholog, Tar DNA-binding homolog (tbph), causes severe locomotion defects in larvae that are media...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Exp Biol
Hauptverfasser: Lembke, Kayly M., Law, Alexander D., Ahrar, Jasmine, Morton, David B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340135/
https://ncbi.nlm.nih.gov/pubmed/30397173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jeb.191106
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