Blockade of Store-Operated Calcium Entry Reduces IL-17/TNF Cytokine-Induced Inflammatory Response in Human Myoblasts

Muscle inflammation as in idiopathic inflammatory myopathies (IIM) leads to muscle weakness, mononuclear cell infiltration, and myofiber dysfunction affecting calcium channels. The effects of interleukin-17A (IL-17) and tumor necrosis factor-α (TNFα) on inflammation and calcium changes were investig...

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Udgivet i:Front Immunol
Main Authors: Beringer, Audrey, Gouriou, Yves, Lavocat, Fabien, Ovize, Michel, Miossec, Pierre
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6339936/
https://ncbi.nlm.nih.gov/pubmed/30693003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.03170
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