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Three-dimensional intact-tissue sequencing of single-cell transcriptional states

Retrieving high-content gene-expression information while retaining three-dimensional (3D) positional anatomy at cellular resolution has been difficult, limiting integrative understanding of structure and function in complex biological tissues. We developed and applied a technology for 3D intact-tis...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Wang, Xiao, Allen, William E., Wright, Matthew A., Sylwestrak, Emily L., Samusik, Nikolay, Vesuna, Sam, Evans, Kathryn, Liu, Cindy, Ramakrishnan, Charu, Liu, Jia, Nolan, Garry P., Bava, Felice-Alessio, Deisseroth, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6339868/
https://ncbi.nlm.nih.gov/pubmed/29930089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aat5691
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