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Neonatal Streptococcus pneumoniae Pneumonia Induces an Aberrant Airway Smooth Muscle Phenotype and AHR in Mice Model

Our previous study showed that neonatal S. pneumoniae infection aggravated airway inflammation and airway hyperresponsiveness (AHR) in an OVA-induced allergic asthma model. As airway smooth muscle (ASM) plays a pivotal role in AHR development, we aim to investigate the effects of neonatal S. pneumon...

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Библиографические подробности
Опубликовано в: :Biomed Res Int
Главные авторы: Peng, Xin, Wu, Yi, Kong, Xiao, Chen, Yunxiu, Tian, Yonglu, Li, Qinyuan, Tian, Xiaoyin, Zhang, Guangli, Ren, Luo, Luo, Zhengxiu
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6339730/
https://ncbi.nlm.nih.gov/pubmed/30723734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1948519
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