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Repurposing triphenylmethane dyes to bind to trimers derived from Aβ
Soluble oligomers of the β-amyloid peptide, Aβ, are associated with the progression of Alzheimer’s disease. Although many small molecules bind to these assemblies, the details of how these molecules interact with Aβ oligomers remain unknown. This paper reports that crystal violet, and other C3 symme...
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| Publicado en: | J Am Chem Soc |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6339561/ https://ncbi.nlm.nih.gov/pubmed/30125493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b06568 |
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