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HIV peptidome-wide association study reveals patient-specific epitope repertoires associated with HIV control
Genetic variation in the peptide-binding groove of the highly polymorphic HLA class I molecules has repeatedly been associated with HIV-1 control and progression to AIDS, accounting for up to 12% of the variation in HIV-1 set point viral load (spVL). This suggests a key role in disease control for H...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6338868/ https://ncbi.nlm.nih.gov/pubmed/30602460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812548116 |
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