Загрузка...

Structural basis for prodrug recognition by the SLC15 family of proton-coupled peptide transporters

A major challenge in drug development is the optimization of intestinal absorption and cellular uptake. A successful strategy has been to develop prodrug molecules, which hijack solute carrier (SLC) transporters for active transport into the body. The proton-coupled oligopeptide transporters, PepT1...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Minhas, Gurdeep S., Newstead, Simon
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338836/
https://ncbi.nlm.nih.gov/pubmed/30602453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1813715116
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!