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Syntheses and cytotoxicity of phosphatidylcholines containing ibuprofen or naproxen moieties

In this study, novel phosphatidylcholines containing ibuprofen or naproxen moieties were synthesized in good yields and high purities. Under the given synthesis conditions, the attached drug moieties racemized, which resulted in the formation of phospholipid diastereomers. The comperative studies of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kłobucki, Marek, Urbaniak, Anna, Grudniewska, Aleksandra, Kocbach, Bartłomiej, Maciejewska, Gabriela, Kiełbowicz, Grzegorz, Ugorski, Maciej, Wawrzeńczyk, Czesław
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338774/
https://ncbi.nlm.nih.gov/pubmed/30659229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36571-1
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