Epstein-Barr Virus Latent Membrane Protein-1 Induces the Expression of SUMO-1 and SUMO-2/3 in LMP1-positive Lymphomas and Cells

Epstein-Barr Virus latent membrane protein-1 (LMP1) interacts with the SUMO-conjugating enzyme Ubc9, which induces protein sumoylation and may contribute to LMP1-mediated oncogenesis. After analyzing human lymphoma tissues and EBV-positive cell lines, we now document a strong correlation between LMP...

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Udgivet i:Sci Rep
Main Authors: Salahuddin, Sadia, Fath, Emma K., Biel, Natalie, Ray, Ashley, Moss, C. Randall, Patel, Akash, Patel, Sheetal, Hilding, Leslie, Varn, Matthew, Ross, Tabithia, Cramblet, Wyatt T., Lowrey, Angela, Pagano, Joseph S., Shackelford, Julia, Bentz, Gretchen L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338769/
https://ncbi.nlm.nih.gov/pubmed/30659232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36312-4
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