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Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease

Human gut microbiota senses its environment and responds by releasing metabolites, some of which are key regulators of human health and disease. In this study, we characterize gut-associated bacteria in their ability to decarboxylate levodopa to dopamine via tyrosine decarboxylases. Bacterial tyrosi...

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書目詳細資料
發表在:Nat Commun
Main Authors: van Kessel, Sebastiaan P., Frye, Alexandra K., El-Gendy, Ahmed O., Castejon, Maria, Keshavarzian, Ali, van Dijk, Gertjan, El Aidy, Sahar
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338741/
https://ncbi.nlm.nih.gov/pubmed/30659181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08294-y
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