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Role of Mitochondria in Ferroptosis

Ferroptosis is a regulated necrosis process driven by iron-dependent lipid peroxidation. Although ferroptosis and cellular metabolism interplay with each other, whether mitochondria are involved in ferroptosis is under debate. Here we demonstrate that mitochondria play a crucial role in cysteine dep...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Gao, Minghui, Yi, Junmei, Zhu, Jiajun, Minikes, Alexander M., Monian, Prashant, Thompson, Craig B., Jiang, Xuejun
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338496/
https://ncbi.nlm.nih.gov/pubmed/30581146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.10.042
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