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Identification, pathophysiology, and clinical implications of primary insulin hypersecretion in nondiabetic adults and adolescents

BACKGROUND. Excessive insulin secretion may lead to glucose dysregulation. Our aim was to identify primary (independent of insulin resistance) insulin hypersecretion in subjects with normal glucose tolerance and its role in the progression of dysglycemia. METHODS. In 1,168 adults, insulin secretion...

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Bibliografske podrobnosti
izdano v:JCI Insight
Main Authors: Tricò, Domenico, Natali, Andrea, Arslanian, Silva, Mari, Andrea, Ferrannini, Ele
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338316/
https://ncbi.nlm.nih.gov/pubmed/30568042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124912
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