Age-related changes in the BACH2 and PRDM1 genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients

BACKGROUND: Age-related genetic changes in lymphocyte subsets are not currently well documented. BACH2 is a transcription factor that plays an important role in immune-mediated homeostasis by tightly regulating PRDM1 expression in both B-cells and T-cells. BACH2 gene expression is highly sensitive t...

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Pubblicato in:BMC Cancer
Autori principali: Chi, Vu Luan Dang, Garaud, Soizic, De Silva, Pushpamali, Thibaud, Vincent, Stamatopoulos, Basile, Berehad, Mimoune, Gu-Trantien, Chunyan, Krayem, Mohammad, Duvillier, Hugues, Lodewyckx, Jean-Nicolas, Willard-Gallo, Karen, Sibille, Catherine, Bron, Dominique
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337793/
https://ncbi.nlm.nih.gov/pubmed/30654767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5276-2
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