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Short Peptides with Uncleavable Peptide Bond Mimetics as Photoactivatable Caspase-3 Inhibitors

Chemical probes that covalently interact with proteases have found increasing use for the study of protease function and localization. The design and synthesis of such probes is still a bottleneck, as the strategies to target different families are highly diverse. We set out to design and synthesize...

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Publicat a:Molecules
Autors principals: Van Kersavond, Tim, Konopatzki, Raphael, Chakrabarty, Suravi, Blank-Landeshammer, Bernhard, Sickmann, Albert, Verhelst, Steven H. L.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337261/
https://ncbi.nlm.nih.gov/pubmed/30626051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24010206
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