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Toward of Safer Phenylbutazone Derivatives by Exploration of Toxicity Mechanism

A drug design for safer phenylbutazone was been explored by reactivity and docking studies involving single electron transfer mechanism, as well as toxicological predictions. Several approaches about its structural properties were performed through quantum chemistry calculations at the B3LYP level o...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Borges, Rosivaldo S., Palheta, Ivanete C., Ota, Sirlene S. B., Morais, Roberto B., Barros, Valéria A., Ramos, Ryan S., Silva, Rai C., Costa, Josivan da S., Silva, Carlos H. T. P., Campos, Joaquín M., Santos, Cleydson B. R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337259/
https://ncbi.nlm.nih.gov/pubmed/30609687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24010143
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